Saturday, September 14, 2013

What is an illegal drug that can wipe your memory clean to a certain extent?

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Jules


lol before you say anything, this is not for me. I'm writing a novel, and one of the character's recent memories are completely wiped clean. After she disappeared for several days, she was found in a car surround by illegal drug paraphanalia, which authorities chalked up to her having memory loss. Any suggestions??
Not to be a pain, but if you could please justify/support your answer or have resources cited so i can make sure that info is solid
thanks for everything =)



Answer
How Marijuana Causes Memory Deficits

ScienceDaily (Aug. 4, 2009) â Memory loss associated with marijuana use is caused by the drugâs interference with the brainâs natural protein synthesis machinery, according to a study published in Nature Neuroscience.

Though it has been documented that marijuana impairs memory, the precise mechanism for this memory impairment was previously unknown. Andrés Ozaita, of the Universitat Pompeu Fabra in Spain, along with colleagues in France and Germany, focused on THC, the main psychoactive chemical compound in marijuana, which acts on a specific class of receptors known as cannabinoid receptors. These receptors are known to affect the connection strength between neurons.

The scientists found that THC increases the activity of a pathway that promotes protein synthesis in the mouse brain. This transient increase of protein synthesis was mediated specifically by cannabinoid receptors expressed on the brainâs inhibitory neurons, and correlated with long-term memory deficits in mice. Interestingly, the authors also found that inhibition of this signaling pathway by rapamycin, an immunosuppressant drug used to prevent organ rejection following transplantation, prevents THC-induced amnesia in mice.

http://www.sciencedaily.com/releases/2009/08/090803123240.htm

A new study finds those who've used a lot of marijuana have worse memories and don't think as quickly.

It's not the first study to suggest pot hurts memory, but the findings are stark.

In one memory test, long-time uses remembered seven of 15 words, on average. Non-users remembered 12 of 15. On a decision-making test, those who had rarely smoked pot had impaired performance 8 percent of time, while long-term tokers had 70 percent impairment.

The results are detailed in the March 14 issue of the journal Neurology.

The study involved 64 people age 17 to 49 selected from a larger study group. They were split into three groups: those who had smoked four or more joints per week for more than 10 years; those who'd been smoking for five to 10 years; and those who had smoked at least once but not more than 20 times and not at all in the past two years.

The middle group consistently scored in between the other two.

"We found that the longer people used marijuana, the more deterioration they had in these cognitive abilities, especially in the ability to learn and remember new information," said Lambros Messinis of the Department of Neurology at the University Hospital of Patras in Patras, Greece

A separate study in Neurology last year found higher blood flow velocity in the marijuana users even a month after they stopped smoking. Researchers said the change could help explain other studies that have revealed memory problems in pot smokers

A Harvard Medical School study in 2003 found lasting memory impairment in people who had started smoking marijuana before age 17, when the brain is still forming.

And research published in November indicated that heavy marijuana use might put adolescents who are genetically predisposed to schizophrenia at greater risk of developing the brain disorder.

Some 3.1 million Americans age 12 and older use marijuana daily or almost daily, according to the National Institute on Drug Abuse. In 2004, 5.6 percent of 12th graders reported daily use of marijuana

http://www.livescience.com/health/060313_pot_brain.html

Marijuana use tied to Memory Loss http://www.theage.com.au/news/world/marijuana-tied-to-memory-loss/2006/03/15/1142098471704.html

Marijuana Proven to Affect Memory

http://dsc.discovery.com/news/2009/08/03/marijuana-memory.html

Marijuana's Memory Loss Caused by Scrambled Neurons
http://www.bloomberg.com/apps/news?pid=newsarchive&sid=adIaujYahQX0

Why should Zimmerman be found guilty just because he followed Martin?




Anonymous


When Zimmerman chose to follow Martin, he was not disobeying a law enforcement officer, he simply ignored the suggestion of a 9-11 dispatcher.

Sure, the fight would not have happened if Zimmerman stayed in his car.

But following that logic, Martin would not have been shot if he didn't punch and beat down Zimmerman.

There was no proof of who started the physical contact, but there was proof that Zimmerman was punched and having his head beat into the concrete. He feared for his life/sever bodily harm and used his gun as a last resort.



Answer
When you're a visitor in a gated community, it's normal for nosy neighbors to butt into your business to find out why they don't recognize you. The usual procedure is for the nosy neighbor to look at you inquiringly and ask, "Can I help you find something?"

The usual response is, "No, that's okay, I'm just visiting my uncle. He lives over on Maple Street. But thanks for asking."

"You're welcome."

It's also normal for security guards and neighborhood watch to be nosy and ask questions.

This happens thousands of times a day, and usually without incident. In fact, most of the time people are grateful because they can't find Maple Street and want to know how to get there. That happens all the time with plumbers, gardeners, the new au pair girl, etc.

Furthermore, it doesn't even need to be a gated community, just a neighborhood where people keep an eye out for each other.

UPDATE

Trayvon Martin was not a "young boy." He was 5'11, 158 pounds. (The news media has repeatedly published pictures showing what he looked like at age 12 and 13.) George Zimmerman was 5'8'', 3 inches shorter.




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